Thinking about a post-pandemic world

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I've been trying to think carefully about what our world will be like once the current pandemic is over.  Most people are rightly focuse...
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Response to Ambur et al.

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 The points in purple are objections raised by Ambur et al . to the hypothesis that the main function of DNA uptake b...

Designing better masks

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Optimizing design of masks to prevent spread of COVID-19: (Originally a series of tweets that came out in the wrong order) 1.   ...

A semi-quantitative framework for long-term thinking about the COVID-19 pandemic

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I think the current rush to invoke extreme flatten-the-curve measures needs to be accompanied by careful thought about what we'll do onc...
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Planning the GTA work

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My goal for the rest of my time in Andrew Lang's GTA lab  is to gather data that constrains estimates of the efficiency of GTA transduct...

Why doesn't all the GTA get taken up?

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I've been modelling the production and uptake of GTA particles in a culture, hoping to understand the cause of the surprising GTA-accumu...

Marc Solioz's 1975 PhD thesis on GTA

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PhD students, don't assume that your thesis will moulder unread in the library.  More than 40 years after he submitted it, I'm readi...

Summary of R. capsulatus Bioscreen growth curves

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The previous post ( GTA competition experiments ) described the results of the follow-up set of R. capsulatus growth curves that I planned a...

GTA competition experiments

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I'm in St. John's for the 'summer'*, doing GTA-related experiments in Andrew Lang's lab at Memorial University of Newfou...

Wait, there's a much simpler explanation! (For CRISPR-Cas, not for GTA)

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I'm in Halifax for a couple of weeks, visiting Ford Doolittle and his philosophical colleagues,  We've spent much of the time consid...

R. capsulatus growth curves in RCV medium

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My upstairs GTA colleague and I were surprised that the Bioscreen growth curves in the previous post didn't show a dip in OD600 of the G...

What can we learn from growth curves?

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Here's the results of the Bioscreen growth curves I ran for Rhodobacter capsulatus strains: Each dot is the mean OD600 of 15 rep...

growth time courses

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In a few weeks I'll be headed for the Maritimes, for the final part of my sabbatical work on Gene Transfer Agent.  But before I leave he...

Phage plaqueing still sucks - what to do now?

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I feel like I've been sucked down a hole of trying to get consistently countable plaques from the Rhodobacter capsulatus phage I'm ...