- We're the best people to do this work. We have a unique combination of wonderful attributes.
- The components of the work are well balanced. None is excessively risky, and later work is not dependent on the success of (or a particular outcome of) earlier work. Our preliminary results confirm that the basic strategy is robust.
- The approach is cost-effective. Using genome sequencing to get answers about recombination is much cheaper than doing it with molecular biology, because of the breadth of information the sequences provide.
- The results will give insights into the molecular mechanism of recombination.
- The work is testing hidden assumptions about recombination. Over the past 60 years, studies of bacterial genetics have been forced to make assumptions about recombination events. These assumptions were reasonable, given the information available, but now we can finally test them.
- The strains we will have sequenced are a resource for mapping clinically important phenotypes. They also provide a gold-standard control dataset for phylogenetic and epidemiological studies that must detect recombination.
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Field of Science
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RFK Jr. is not a serious person. Don't take him seriously.1 month ago in Genomics, Medicine, and Pseudoscience
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The Site is Dead, Long Live the Site2 years ago in Catalogue of Organisms
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The Site is Dead, Long Live the Site2 years ago in Variety of Life
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What I read 20194 years ago in Angry by Choice
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Histological Evidence of Trauma in Dicynodont Tusks6 years ago in Chinleana
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Posted: July 21, 2018 at 03:03PM6 years ago in Field Notes
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Why doesn't all the GTA get taken up?6 years ago in RRResearch
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Harnessing innate immunity to cure HIV8 years ago in Rule of 6ix
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post doc job opportunity on ribosome biochemistry!9 years ago in Protein Evolution and Other Musings
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Blogging Microbes- Communicating Microbiology to Netizens10 years ago in Memoirs of a Defective Brain
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Re-Blog: June Was 6th Warmest Globally10 years ago in The View from a Microbiologist
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The Lure of the Obscure? Guest Post by Frank Stahl12 years ago in Sex, Genes & Evolution
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Lab Rat Moving House13 years ago in Life of a Lab Rat
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Goodbye FoS, thanks for all the laughs13 years ago in Disease Prone
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Slideshow of NASA's Stardust-NExT Mission Comet Tempel 1 Flyby13 years ago in The Large Picture Blog
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in The Biology Files
Not your typical science blog, but an 'open science' research blog. Watch me fumbling my way towards understanding how and why bacteria take up DNA, and getting distracted by other cool questions.
Last paragraph of the NIH proposal
I need to get it written in the next half hour, but my brain is jammed. Points it should make:
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